GLP-1 frequently asked questions

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of medications that mimic a natural hormone to lower blood sugar, slow stomach emptying, and reduce appetite. The most common GLP-1 drugs include Ozempic, Wegovy, Mounjaro, Zepbound, and Rybelsus.

GLP-1 receptor agonists slow gastric emptying, increase satiety, and reduce hunger signals in the brain. Most patients lose 12–22% of their body weight over 12–18 months on Wegovy or Zepbound.

Both contain the same active ingredient (semaglutide) made by Novo Nordisk. Ozempic is FDA-approved for type 2 diabetes; Wegovy is FDA-approved for chronic weight management. Wegovy has higher max dose (2.4 mg/wk vs 2 mg/wk).

GLP-1 drugs have been used safely for over 15 years for type 2 diabetes. Common side effects are GI-related (nausea, constipation). Rare risks include pancreatitis, gallbladder issues, and a boxed warning for thyroid C-cell tumors based on rat studies.

Cash price ranges from $349/mo (Zepbound via telehealth) to $1,349/mo (Wegovy retail). Compounded GLP-1 from telehealth providers like Henry Meds or Mochi can be as low as $199/mo. Use our cost calculator to estimate your price.

Coverage varies widely. Most commercial plans cover GLP-1 for type 2 diabetes (Ozempic, Mounjaro). Weight-loss-only indications (Wegovy, Zepbound) often require prior auth and BMI ≥ 30. Use our insurance lookup to check your specific plan.

Both Novo Nordisk (Ozempic/Wegovy) and Eli Lilly (Mounjaro/Zepbound) offer copay cards that can reduce out-of-pocket cost to $25–$549/mo depending on plan and eligibility. See drug pages for current offers.

Compounded GLP-1 is a custom-mixed version of the active drug, produced by a 503A or 503B pharmacy. It is NOT FDA-reviewed for safety or efficacy. It became available during the official drug shortage but may face restrictions as supply normalizes.

Yes — under FDA shortage exceptions, 503A pharmacies can legally compound semaglutide/tirzepatide. The FDA has issued warnings about non-compliant compounders. Always verify your telehealth provider works with a state-licensed pharmacy.

It depends on your risk tolerance. Compounded options cost 40–70% less than FDA-approved versions but lack FDA oversight on potency and purity. Talk to a licensed clinician about whether compounded medication is right for you.

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Every clinical claim is reviewed by a licensed clinician. Meet our medical reviewers on the authors page. We re-verify pricing data monthly with each provider.

No. GLP1Zoom is an editorial comparison site, not an insurance company or pharmacy. We help you find the lowest GLP-1 prices but cannot prescribe medication, process claims, or provide medical advice.