GLP-1 & weight-loss clinical trials in Florida
16 GLP-1 or weight-loss trials are recruiting in Florida as of July 14, 2026, with sites in Clearwater, Daytona Beach, Doral, Fleming Island, Fort Myers and more. Many studies reimburse time and travel — the amount is set by each study and confirmed when you contact the team.
- A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Phase 2 · ~1481 participants · NCT06143956
Studied intervention: Tirzepatide
Florida sites: Fleming Island, Miami, Miami Lakes, New Port Richey, Orlando, The Villages
- A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
Phase 4 · ~200 participants · NCT06864026
Studied intervention: Tirzepatide
Florida sites: Kissimmee, Margate, Miami Beach, Palm Beach Gardens, Tampa
- The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity
Phase 4 · ~40 participants · NCT07218445
Studied intervention: Tirzepatide
Florida site: Jacksonville
- A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease
Phase 2 · ~465 participants · NCT06717698
Studied intervention: Semaglutide
Florida sites: Fleming Island, Hollywood, Saint Augustine, Winter Haven
- A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity
Phase 2 · ~230 participants · NCT07639021
Studied intervention: Semaglutide, Semaglutide placebo
Florida sites: Hollywood, Miramar, Ocoee
- A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet
Phase 1 · ~80 participants · NCT07184086
Studied intervention: CagriSema (Cagrilintide B + semaglutide I)
Florida site: Orlando
- Efficacy and Safety of KAI-9531 Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
Phase 3 · ~1200 participants · NCT07284979
Studied intervention: Semaglutide
Florida site: Orange City
- Effects of Glucagon-like Peptide-1 (GLP-1) Agonist in Neuro-reproductive Function in Obese Adolescent Females With Polycystic Ovary Syndrome (PCOS)
Interventional · ~20 participants · NCT07169136
Studied intervention: GLP-1 Receptor Agonists
Florida site: Jacksonville
- A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Phase 3 · ~2500 participants · NCT07564414
Studied intervention: Semaglutide
Florida sites: Clearwater, Fleming Island, Jacksonville, Miami, Miramar, Ocoee, Oviedo, Pembroke Pines
- A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
Phase 3 · ~1000 participants · NCT07202884
Studied intervention: Orforglipron
Florida sites: Fort Myers, Lake Worth, Miami, Panama City
- A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
Phase 4 · ~200 participants · NCT06857942
Studied intervention: Tirzepatide
Florida sites: Hialeah, Hollywood, Tampa, Wellington
- Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Phase 3 · ~290 participants · NCT06937099
Studied intervention: Tirzepatide
Florida sites: Miami, Orlando, Pensacola, Sunrise
- A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Phase 3 · ~460 participants · NCT07253285
Studied intervention: Cagrilintide, Semaglutide, Placebo cagrilintide, Placebo semaglutide
Florida sites: Hollywood, Jacksonville, Weston
- A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain
Phase 3 · ~586 participants · NCT07035093
Studied intervention: Retatrutide
Florida sites: Daytona Beach, Miami, St. Petersburg, Tampa, The Villages, Winter Park
- Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Phase 3 · ~350 participants · NCT06937086
Studied intervention: Tirzepatide
Florida sites: Miami, Orlando, Pensacola, Sunrise
- Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss
Phase 2 · ~200 participants · NCT07446998
Studied intervention: Semaglutide (Wegovy) weekly injection
Florida sites: Doral, Miami
What joining a GLP-1 trial in Florida actually involves
Every study above is registered on ClinicalTrials.gov, the US National Library of Medicine's public registry, and each link goes straight to that record — the one place the eligibility criteria, the schedule of visits and the contact details are kept current. A recruiting listing means the study is actively enrolling; it does not mean you are eligible until the study team screens you.
- Reimbursement is not the same as payment. Many studies cover time and travel, but the amount is set per study and confirmed by the team — treat any specific figure you see elsewhere as unverified until they tell you.
- You may receive a placebo. Most of these are randomized, so joining is not a guaranteed route to the active drug. That is worth weighing if your goal is treatment rather than contributing to the evidence.
- Trial participation is free to join and separate from a prescription. If your aim is to start a GLP-1 now, compare the cash-pay routes instead — trials are a different path with a different purpose.
Source: ClinicalTrials.gov (US National Library of Medicine), public-domain data, snapshot July 14, 2026. This is not medical advice or a recruitment service — confirm status, eligibility, and compensation on each linked ClinicalTrials.gov record and discuss any trial with your clinician.