Prior authorization is an approval step before your insurance pays for a specific drug. For GLP-1 medications, PA is the rule, not the exception.
What insurance looks for
- BMI ≥ 30 (or ≥ 27 with comorbidity) for weight-loss indications.
- Documented prior weight-loss attempts (diet, exercise, sometimes prior medications).
- For diabetes indications: HbA1c documentation and step-therapy history.
If denied
- File an appeal — appeal success rates run 40–60% with proper documentation.
- Use our appeal letter generator to auto-draft a payer-specific letter with the right medical-necessity citations.
- Some plans allow peer-to-peer review where your prescriber speaks directly with the insurer's medical director.
Related resources
More in Cost & insurance
How much does GLP-1 cost without insurance?
Cash price ranges from about $299/month for Zepbound via telehealth to $1,349/month at retail for Wegovy. Compounded options can be lower.
Does insurance cover GLP-1 for weight loss?
Most commercial plans cover GLP-1 for type 2 diabetes. Weight-loss-only indications often require prior authorization and a BMI ≥ 30.
How do manufacturer savings cards work?
Novo Nordisk and Eli Lilly offer copay cards that can reduce out-of-pocket cost to $25–$499/month depending on plan and eligibility.