With insurance
If your plan covers semaglutide, your out-of-pocket cost is a copay set by your formulary tier — often $25–$100/month, and as low as $0–$25 with a manufacturer savings card if you have commercial (non-government) insurance. Ozempic is more widely covered (type 2 diabetes) than Wegovy (weight management), and coverage varies by plan. See our payer coverage pages.
Without insurance (cash-pay)
Uninsured, the manufacturer savings cards do not apply. The cheapest FDA-approved routes are the oral Wegovy pill from about $149/month and NovoCare self-pay injectable Wegovy around $349/month for maintenance ($ 199/month introductory). Brand Ozempic has no comparable low cash price for weight loss.
Compounded semaglutide
Compounded semaglutide via licensed telehealth runs $69–$300/mo, but it is not FDA-approved as a finished drug — the FDA does not review it for safety, potency, or quality, and it should only come from a licensed US 503A/503B pharmacy. Read is compounded semaglutide safe & legal? before choosing this route. This is also what sits behind any advertised “generic semaglutide price” — no FDA-approved generic exists yet, and when GLP-1 patents actually expire covers why.
Which route is cheapest for you
It depends on insurance: with coverage, a savings card usually wins; without it, the oral pill or NovoCare self-pay are the cheapest FDA-approved options. For the full route-by-route ranking, see the cheapest way to get semaglutide. Not sure where to start? Take our 60-second quiz.