Yes — Wegovy is kept in the refrigerator until it is needed, and never frozen. Its label then allows: single-dose pen or single-dose syringe: up to 28 days at 46–86°F (8–30°C), before the cap comes off; four-dose FlexTouch pen: 56 days after first use, at room temperature or refrigerated.
What if Wegovy was left out of the fridge?
It is generally still usable within the room-temperature allowance on the label above. Past that allowance, or after heat above the labeled limit or any freezing, it should not be used. If you are unsure how long it sat out or how warm it got, call your pharmacist before injecting rather than guessing.
Traveling with Wegovy
For trips, carry Wegovy in an insulated bag with a cold pack (not directly touching the pen, to avoid freezing) and keep it in your carry-on, never a checked bag or a hot car. At your destination, refrigerate any unopened pens. Airport security allows medically necessary medication and cold packs; a pharmacy label or prescription can smooth the screening.
When to take Wegovy
Any time of day, with or without food. Same day each week. If you miss a dose: If your next scheduled dose is more than 2 days (48 hours) away, inject the missed dose as soon as possible. If it is less than 2 days away, skip it and inject on your usual day.
Common questions
Does Wegovy need to be refrigerated?
Unopened Wegovy is kept in the refrigerator (36–46°F / 2–8°C). Its label then allows a defined stretch outside it: up to 28 days at 46–86°F (8–30°C), before the cap comes off. Never freeze an injectable pen; if it freezes, do not use it.
How long can Wegovy stay out of the fridge?
Up to 28 days at 46–86°F (8–30°C), before the cap comes off, per the Wegovy label (single-dose pen or single-dose syringe). Limits differ by drug — Trulicity allows 14 days, the tirzepatide single-dose pens 21, a Wegovy pen 28 out of the fridge, and an Ozempic pen 56 from first use — so do not carry a figure over from a previous medication. If you are unsure how long yours sat out, ask your pharmacist before using it.