Yes — Trulicity is kept in the refrigerator until it is needed, and never frozen. Its label then allows: prefilled pen: up to 14 days total at room temperature — the shortest allowance in the class.
What if Trulicity was left out of the fridge?
It is generally still usable within the room-temperature allowance on the label above. Past that allowance, or after heat above the labeled limit or any freezing, it should not be used. If you are unsure how long it sat out or how warm it got, call your pharmacist before injecting rather than guessing.
Traveling with Trulicity
For trips, carry Trulicity in an insulated bag with a cold pack (not directly touching the pen, to avoid freezing) and keep it in your carry-on, never a checked bag or a hot car. At your destination, refrigerate any unopened pens. Airport security allows medically necessary medication and cold packs; a pharmacy label or prescription can smooth the screening.
When to take Trulicity
Once weekly, any time of day, with or without food If you miss a dose: Inject the missed dose as soon as possible only if there are at least 3 days (72 hours) until your next scheduled dose. Otherwise skip it and inject on your usual day.
Common questions
Does Trulicity need to be refrigerated?
Unopened Trulicity is kept in the refrigerator (36–46°F / 2–8°C). Its label then allows a defined stretch outside it: up to 14 days total at room temperature — the shortest allowance in the class. Never freeze an injectable pen; if it freezes, do not use it.
How long can Trulicity stay out of the fridge?
Up to 14 days total at room temperature — the shortest allowance in the class, per the Trulicity label (prefilled pen). Limits differ by drug — Trulicity allows 14 days, the tirzepatide single-dose pens 21, a Wegovy pen 28 out of the fridge, and an Ozempic pen 56 from first use — so do not carry a figure over from a previous medication. If you are unsure how long yours sat out, ask your pharmacist before using it.